Article
The interplay between host and viral factors in shaping the outcome of cytomegalovirus infection.
Immunology and cell biology - 1 Jan 2007
Scalzo Anthony A, Corbett Alexandra J, Rawlinson William D, Scott Gillian M, Degli-Esposti Mariapia A
Abstract excerpt
Cytomegalovirus (CMV) remains a major human pathogen causing significant morbidity and mortality in immunosuppressed or immunoimmature individuals. Although significant advances have been made in dissecting out certain features of the host response to human CMV (HCMV) infection, the strict species specificity of CMVs means that most aspects of antiviral immunity are best assessed in animal models. The mouse model...
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