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Article

Maneuvering for advantage: the genetics of mouse susceptibility to virus infection.

Trends in genetics : TIG - 1 Aug 2003

Lee Seung-Hwan, Dimock Ken, Gray Douglas A, Beauchemin Nicole, Holmes Kathryn V, Belouchi Majid, Realson John, Vidal Silvia M

Abstract excerpt

Genetic studies of host susceptibility to infection contribute to our understanding of an organism's response to pathogens at the immunological, cellular, and molecular levels. In this review we describe how the study of host genetics in mouse models has helped our understanding of host defense mechanisms against viral infection, and how this knowledge can be extended to human infections. We focus especially on...

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Source

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Identifiers

PMID: 12902163
DOI: 10.1016/S0168-9525(03)00172-0
PMCID: PMC7127612

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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