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The Presence of Capsule inCryptococcus neoformansInfluences the Gene Expression Profile in Dendritic Cells during Interaction with the Fungus

5 Feb 2008

Abstract excerpt

The aim of this investigation was to study the effect of polysaccharide capsule on the gene expression in dendritic cells (DC) during their interaction with Cryptococcus neoformans. To this end, we used an encapsulated virulent strain of C. neoformans and a cap59 gene-disrupted acapsular avirulent strain derived from the same genetic background. DC were exposed to encapsulated and acapsular C. neoformans strains...

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PMID: 18250173
DOI: 10.1128/iai.01184-07

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