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Article

Acapsular Cryptococcus neoformans activates the NLRP3 inflammasome.

Microbes and infection - 1 Oct 2014

Guo Caiqin, Chen Mingkuan, Fa Zhenzong, Lu Ailing, Fang Wei, Sun Bing, Chen Changbin, Liao Wanqing, Meng Guangxun

Abstract excerpt

Cryptococcus neoformans (C. neoformans) is an opportunistic fungal pathogen that mainly infects immunocompromised individuals such as AIDS patients. Although cell surface receptors for recognition of C. neoformans have been studies intensively, cytoplasmic recognition of this pathogen remains unclear. As an important detector of pathogen infection, inflammasome can sense and get activated by infection of various...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25193031
DOI: 10.1016/j.micinf.2014.08.013

Genes

NLRP3
AIM2
NLRC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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