Cryptococcus neoformans gene expression during murine macrophage infection.

doi:10.1128/EC.4.8.1420-1433.2005

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Cryptococcus neoformans gene expression during murine macrophage infection.

Eukaryotic cell - 1 Aug 2005

Fan Weihua, Kraus Peter R, Boily Marie-Josee, Heitman Joseph

Abstract excerpt

The fungal pathogen Cryptococcus neoformans survives phagocytosis by macrophages and proliferates within, ultimately establishing latent infection as a facultative intracellular pathogen that can escape macrophage control to cause disseminated disease. This process is hypothesized to be important for C. neoformans pathogenesis; however, it is poorly understood how C. neoformans adapts to and overcomes the hostile...

Topics

Animals
BALB 3T3 Cells
Cryptococcus neoformans
Gene Expression Profiling
Gene Expression Regulation, Fungal
Genes, Fungal
Green Fluorescent Proteins
Infections
Lymphoma, Large B-Cell, Diffuse
Macrophages
Membrane Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Microarray Analysis

Phagocytosis

Phenotype

Reverse Transcriptase Polymerase Chain Reaction

Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 16087747
DOI: 10.1128/EC.4.8.1420-1433.2005
PMCID: PMC1214536

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-16087747-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cryptococcus neoformans gene expression during murine macrophage infection.PMID 16087747Read ↗

Macrophage Mitochondrial and Stress Response to Ingestion of Cryptococcus neoformansSemantic proximity Read ↗

The transcriptional response of Cryptococcus neoformans to ingestion by Acanthamoeba castellanii and macrophages provides insights into the evolutionary adaptation to the mammalian host.Semantic proximity Read ↗

Transcriptional response of Candida albicans upon internalization by macrophages.Semantic proximity Read ↗

Mucor circinelloides Thrives inside the Phagosome through an Atf-Mediated Germination PathwaySemantic proximity Read ↗

Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP.Semantic proximity Read ↗

Adaptation of Cryptococcus neoformans to Mammalian Hosts: Integrated Regulation of Metabolism and VirulenceSemantic proximity Read ↗

Iron‐regulated transcription and capsule formation in the fungal pathogen Cryptococcus neoformansSemantic proximity Read ↗

The Dynamics of Cryptococcus neoformans Cell and Transcriptional Remodeling during InfectionSemantic proximity Read ↗

Transcriptional network of multiple capsule and melanin genes governed by the Cryptococcus neoformans cyclic AMP cascade.Semantic proximity Read ↗

Candida auris —macrophage cellular interactions and transcriptional responseSemantic proximity Read ↗

Interactions of Both Pathogenic and Nonpathogenic CUG Clade Candida Species with Macrophages Share a Conserved Transcriptional LandscapeSemantic proximity Read ↗

Cryptococcus gattii strains with a high phagocytosis phenotype by macrophages display high pathogenicity at the early stage of infection in vivo.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.