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Article

The Cryptococcus neoformans Capsule: a Sword and a Shield

1 Jul 2012

Abstract excerpt

The human fungal pathogen Cryptococcus neoformans is characterized by its ability to induce a distinct polysaccharide capsule in response to a number of host-specific environmental stimuli. The induction of capsule is a complex biological process encompassing regulation at multiple steps, including the biosynthesis, transport, and maintenance of the polysaccharide at the cell surface. By precisely regulating the...

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PMID: 22763631
DOI: 10.1128/cmr.00001-12

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