Article
Cardiovascular disease risk prediction with and without knowledge of genetic variation at chromosome 9p21.3.
Annals of internal medicine - 20 Jan 2009
Paynter Nina P, Chasman Daniel I, Buring Julie E, Shiffman Dov, Cook Nancy R, Ridker Paul M
Abstract excerpt
BACKGROUND: Although genetic variation at chromosome 9p21.3 is associated with incident cardiovascular disease, it is unclear whether screening for this polymorphism improves risk prediction. OBJECTIVE: To determine whether knowledge of variation at chromosome 9p21.3 provides predictive information beyond that from other readily available risk factors. DESIGN: Prospective cohort study. SETTING: United States....
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