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Article

Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice.

Molecular and cellular neurosciences - 1 Mar 2008

Christoph Thomas, Bahrenberg Gregor, De Vry Jean, Englberger Werner, Erdmann Volker A, Frech Moritz, Kögel Babette, Röhl Thomas, Schiene Klaus, Schröder Wolfgang, Seibler Jost, Kurreck Jens

Abstract excerpt

The function of the transient receptor potential vanilloid 1 (TRPV1) cation channel was analyzed with RNA interference technologies and compared to TRPV1 knockout mice. Expression of shRNAs targeting TRPV1 in transgenic (tg) mice was proven by RNase protection assays, and TRPV1 downregulation was...

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Source

Identifiers

PMID: 18249134
DOI: 10.1016/j.mcn.2007.12.006

Genes

TRPV1
TRPV3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18249134-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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