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Article

The association of polymorphisms of TLR4 and CD14 genes with susceptibility to sepsis in a Chinese population.

BMC medical genetics - 14 Nov 2014

Wang Haiyan, Wei Yesheng, Zeng Yi, Qin Yueqiu, Xiong Bin, Qin Gang, Li Jun, Hu Donghai, Qiu Xiaowen, Sooranna Suren R, Pinhu Liao

Abstract excerpt

BACKGROUND: Sepsis is now the leading cause of death in the non-cardiovascular intensive care unit (ICU). Recent research suggests that sepsis is likely to be due to an interaction between genetic and environmental factors. Genetic mutations of toll-like receptor 4 (TLR4) and cluster of differentiation 14 (CD14) genes are involved in the immune and (or) inflammatory response. These may contribute to the...

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Identifiers

PMID: 25394369
DOI: 10.1186/s12881-014-0123-4
PMCID: PMC4411696

Genes

TLR4

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Source receipt: pubmed, retrieved 7 Sept 2026.

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