Article
Atrial natriuretic peptide and osteopontin are useful markers of cardiac disorders in mice.
Comparative medicine - 1 Dec 2007
Schoensiegel Frank, Bekeredjian Raffi, Schrewe Anja, Weichenhan Dieter, Frey Norbert, Katus Hugo A, Ivandic Boris T
Abstract excerpt
Biomarkers are not established for cardiovascular phenotyping in mice. We compared the use of echocardiography with the determination of N-terminal propeptide of the atrial natriuretic peptide (Nt-proANP) and osteopontin (Opn). We measured plasma Nt-proANP and Opn levels in (1) the inbred strains C57BL/6, BALB/c, C3H/He, DBA/2, FVB/N, 129S1/Sv; (2) a surgical model of nonischemic myocardial infarction; and (3)...
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