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Article

High throughput phenotyping of left and right ventricular cardiomyopathy in calcineurin transgene mice.

The international journal of cardiovascular imaging - 1 Apr 2015

Moreth Kristin, Afonso Luciana Caminha, Fuchs Helmut, Gailus-Durner Valérie, Katus Hugo A, Bekeredjian Raffi, Lehman Lorenz, Hrabě de Angelis Martin

Abstract excerpt

Consistent protocols for the assessment of diastolic and systolic cardiac function to assure the comparability of existing data on preclinical models are missing. Calcineurin transgene (CN) mice are a preclinical model for hypertrophic and failing hearts. We aimed at evaluating left and right ventricular structural and functional remodeling in CN hearts with an optimized phenotyping protocol. We developed a...

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Share to Calcineurin
Share to Echocardiography, Doppler

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hypertrophy, Left Ventricular

Share to Ventricular Dysfunction, Left

Share to Ventricular Function, Right

Share to Ventricular Myosins

Share to Ventricular Remodeling

Source

Identifiers

PMID: 25627778
DOI: 10.1007/s10554-015-0596-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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