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Article

Genetic interactions of the Aspergillus nidulans atmAATM homolog with different components of the DNA damage response pathway.

Genetics - 1 Feb 2008

Malavazi Iran, Lima Joel Fernandes, de Castro Patrícia Alves, Savoldi Marcela, de Souza Goldman Maria Helena, Goldman Gustavo Henrique

Abstract excerpt

Ataxia telangiectasia mutated (ATM) is a phosphatidyl-3-kinase-related protein kinase that functions as a central regulator of the DNA damage response in eukaryotic cells. In humans, mutations in ATM cause the devastating neurodegenerative disease ataxia telangiectasia. Previously, we characterized the homolog of ATM (AtmA) in the filamentous fungus Aspergillus nidulans. In addition to its expected role in the...

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Source

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Identifiers

PMID: 18245360
DOI: 10.1534/genetics.107.080879
PMCID: PMC2248346

Genes

ATM
ATR
WEE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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