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Article

ATM: genome stability, neuronal development, and cancer cross paths.

Advances in cancer research - 1 Jan 2001

Shiloh Y, Kastan M B

Abstract excerpt

One of the cornerstones of the web of signaling pathways governing cellular life and differentiation is the DNA damage response. It spans a complex network of pathways, ranging from DNA repair to modulation of numerous processes in the cell. DNA double-strand breaks (DSBs), which are formed as a result of genotoxic stress or normal recombinational processes, are extremely lethal lesions that rapidly mobilize this...

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PMID: 11665719
DOI: 10.1016/s0065-230x(01)83007-4

Genes

ATM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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