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Article

The role of ATM and DNA damage in neurons: upstream and downstream connections.

DNA repair - 1 Aug 2013

Herrup Karl, Li Jiali, Chen Jianmin

Abstract excerpt

ATM (ataxia-telangiectasia mutated) is a large protein kinase whose best-known function is as a participant in the process of DNA damage repair, specifically lesions that result in double strand breaks. In the cells of the nervous system, however, the symptoms of children with ataxia-telangiectasia and the phenotypes of mice with engineered mutations in their ATM gene argue for a broader range of protein...

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Source

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Identifiers

PMID: 23680599
DOI: 10.1016/j.dnarep.2013.04.012
PMCID: PMC3720697

Genes

ATM
HDAC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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