Article
Atm and c-Abl cooperate in the response to genotoxic stress during nervous system development.
Brain research. Developmental brain research - 10 Oct 2003
Miller Heather L, Lee Youngsoo, Zhao Jingfeng, Chong Miriam J, McKinnon Peter J
Abstract excerpt
The c-Abl proto-oncogene is a target of the ATM kinase after DNA double strand breaks, although the physiological significance of these signaling events is not clear. Therefore, to delineate the roles of c-Abl and Atm during mouse development we generated mice with combinations of c-Abl and Atm m...
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