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Article

<i>PATZ1</i> gene has a critical role in the spermatogenesis and testicular tumours

4 Feb 2008

Abstract excerpt

PATZ1 is a recently discovered zinc finger protein that, due to the presence of the POZ domain, acts as a transcriptional repressor affecting the basal activity of different promoters. To gain insights into its biological role, we generated mice lacking the PATZ1 gene. Male PATZ1(-/-) mice were unfertile, suggesting a crucial role of this gene in spermatogenesis. Consistently, most of adult testes from these mice...

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PMID: 18241078
DOI: 10.1002/path.2323

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<i>PATZ1</i> gene has a critical role in the spermatogenesis and testicular tumoursPMID 18241078Read ↗

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