GATA-1 mutation alters the spermatogonial phase and steroidogenesis in adult mouse testis.

doi:10.1016/j.mce.2021.111519

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Article

GATA-1 mutation alters the spermatogonial phase and steroidogenesis in adult mouse testis.

Molecular and cellular endocrinology - 15 Feb 2022

Gonçalves Matheus Felipe Fonseca, Lacerda Samyra Maria Dos Santos Nassif, Lara Nathália de Lima E Martins, Oliveira Carolina Felipe Alves de, Figueiredo André Felipe Almeida, Brener Marcos Rocha Gouvêa, Cavalcante Marina Alcântara, Santos Anderson Kenedy, Campolina-Silva Gabriel Henrique, Costa Vivian Vasconcelos, Santana Ana Clara Campideli, Lopes Roberta Araújo, Szawka Raphael Escorsim, Costa Guilherme Mattos Jardim

Abstract excerpt

GATA-1 is a transcription factor from the GATA family, which features zinc fingers for DNA binding. This protein was initially identified as a crucial regulator of blood cell differentiation, but it is currently known that the Gata-1 gene expression is not limited to this system. Although the testis is also a site of significant GATA-1 expression, its role in testicular cells remains considerably unexplored. In...

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PMID: 34843900
DOI: 10.1016/j.mce.2021.111519

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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