Article
SPOC1 (PHF13) is required for spermatogonial stem cell differentiation and sustained spermatogenesis.
Journal of cell science - 15 Sept 2011
Bördlein Annegret, Scherthan Harry, Nelkenbrecher Claudia, Molter Tina, Bösl Michael R, Dippold Christine, Birke Kerstin, Kinkley Sarah, Staege Hannah, Will Hans, Winterpacht Andreas
Abstract excerpt
SPOC1 (PHF13) is a recently identified protein that has been shown to dynamically associate with somatic chromatin, to modulate chromatin compaction and to be important for proper cell division. Here, we report on the expression of SPOC1 in promyelocytic leukaemia zinc finger (PLZF)-positive undifferentiated spermatogonial stem cells (SSCs) of the mouse testis. To investigate further the biological function of...
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