Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Embryonic defects and growth alteration in mice with homozygous disruption of the Patz1 gene.

Journal of cellular physiology - 1 Mar 2013

Valentino Teresa, Palmieri Dario, Vitiello Michela, Simeone Antonio, Palma Giuseppe, Arra Claudio, Chieffi Paolo, Chiariotti Lorenzo, Fusco Alfredo, Fedele Monica

Abstract excerpt

PATZ1 is an emerging cancer-related gene coding for a POZ/AT-hook/kruppel Zinc finger transcription factor, which is lost or misexpressed in human neoplasias. Here, we investigated its role in development exploring wild-type and Patz1-knockout mice during embryogenesis. We report that the Patz1 gene is ubiquitously expressed at early stages of development and becomes more restricted at later stages, with high...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle
Share to Central Nervous System

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Embryonic Development

Share to Fetal Growth Retardation

Share to Gene Expression Regulation, Developmental

Share to Mice, Knockout

Share to Neoplasm Proteins

Share to Repressor Proteins

Source

Identifiers

PMID: 22886576
DOI: 10.1002/jcp.24174

Genes

PATZ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Embryonic defects and growth alteration in mice with homozygous disruption of the Patz1 gene.PMID 22886576Read ↗

<i>PATZ1</i> gene has a critical role in the spermatogenesis and testicular tumoursSemantic proximity Read ↗

Miz1 is required for early embryonic development during gastrulation.Semantic proximity Read ↗

PATZ1 acts as a tumor suppressor in thyroid cancer via targeting p53-dependent genes involved in EMT and cell migrationSemantic proximity Read ↗

Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development.Semantic proximity Read ↗

The Polycomb Group Protein Pcgf1 Is Dispensable in Zebrafish but Involved in Early Growth and Aging.Semantic proximity Read ↗

POZ/BTB and AT-hook-containing zinc finger protein 1 (PATZ1) inhibits endothelial cell senescence through a p53 dependent pathwaySemantic proximity Read ↗

Members of the <i>Plag</i> gene family are expressed in complementary and overlapping regions in the developing murine nervous systemSemantic proximity Read ↗

Analyses of Conditional Knockout Mice for Pogz, a Responsible Gene for Neurodevelopmental Disorders, in Excitatory and Inhibitory Neurons in the BrainSemantic proximity Read ↗

Functional roles of neural aPKCs in mouse brain development and survivalSemantic proximity Read ↗

Polo-like kinase 1 is essential for early embryonic development and tumor suppression.Semantic proximity Read ↗

Conserved Roles of Sp1 in Zebrafish Development and Early OrganogenesisSemantic proximity Read ↗

Zeb1 links epithelial-mesenchymal transition and cellular senescence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.