Article
Association of the HLA-DRB1 gene with premature death, particularly from cardiovascular disease, in patients with rheumatoid arthritis and inflammatory polyarthritis.
Arthritis and rheumatism - 1 Feb 2008
Farragher Tracey M, Goodson Nicola J, Naseem Haris, Silman Alan J, Thomson Wendy, Symmons Deborah, Barton Anne
Abstract excerpt
OBJECTIVE: To examine the role of the variants of the PTPN22 and HLA-DRB1 genes as predictors of mortality in inflammatory polyarthritis (IP) and rheumatoid arthritis (RA). METHODS: Patients were recruited from a primary care-based inception cohort of patients with IP and were followed up prospectively. For patients who died, the cause and date of death was obtained. Cox proportional hazards regression models...
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