Article
HLA-DRB1 and persistent chronic inflammation contribute to cardiovascular events and cardiovascular mortality in patients with rheumatoid arthritis.
Arthritis and rheumatism - 15 Feb 2007
Gonzalez-Gay Miguel A, Gonzalez-Juanatey Carlos, Lopez-Diaz Maria J, Piñeiro Angela, Garcia-Porrua Carlos, Miranda-Filloy Jose A, Ollier William E R, Martin Javier, Llorca Javier
Abstract excerpt
OBJECTIVE: Cardiovascular (CV) disease is the most common cause of mortality in patients with rheumatoid arthritis (RA). We assessed the contribution of epidemiologic features, clinical features, routine laboratory markers of inflammation, and HLA-DRB1 alleles to CV mortality in patients with RA prospectively followed at a single referral center in Spain. METHODS: Patients fulfilling the 1987 American College of...
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