Article
Prognostic value of pre-surgical plasma PAI-1 (plasminogen activator inhibitor-1) levels in breast cancer.
Thrombosis research - 1 Sept 2009
Palmirotta Raffaele, Ferroni Patrizia, Savonarola Annalisa, Martini Francesca, Ciatti Filippo, Laudisi Anastasia, Sini Valentina, Del Monte Girolamo, Guadagni Fiorella, Roselli Mario
Abstract excerpt
INTRODUCTION: Plasminogen activator inhibitor (PAI-1) may have an independent prognostic value in breast cancer (BC). PAI-1 4G/5G polymorphism may have significance for antigen expression. Thus, we analyzed the possible associations between PAI-1 4G/5G polymorphism, plasma PAI-1 levels, and clinicopathological features of breast cancer (BC) patients. PATIENTS AND METHODS: PAI-1 4G/5G polymorphism (both on...
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