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Article

SDF-1alpha G801A polymorphism predicts lymph node metastasis in stage T3 colorectal cancer.

Annals of surgical oncology - 1 Aug 2009

Chang Shih-Ching, Lin Pei-Ching, Yang Shung-Haur, Wang Huann-Sheng, Li Anna Fen-Yau, Lin Jen-Kou

Abstract excerpt

BACKGROUND: The SDF-1/CXCR4 axis plays an important role in cancer metastasis. SDF1alpha genetic polymorphisms, including SDF1alpha-G801A, have been associated with increased cancer risk and may be predictive of distant metastasis. The present study compared the frequency of 6 SDF1alpha single-nucleotide polymorphisms (SNPs) in patients with colorectal cancer (CRC) with and without lymph node (LN) metastasis and...

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Source

Identifiers

PMID: 19472013
DOI: 10.1245/s10434-009-0501-x

Genes

CXCR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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