Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Ablation of the CDP/Cux Protein C Terminus Results in Hair Cycle Defects and Reduced Male Fertility

1 Mar 2002

Abstract excerpt

Murine CDP/Cux, a homologue of the Drosophila Cut homeoprotein, modulates the promoter activity of cell cycle-related and cell-type-specific genes. CDP/Cux interacts with histone gene promoters as the DNA binding subunit of a large nuclear complex (HiNF-D). CDP/Cux is a ubiquitous protein containing four conserved DNA binding domains: three Cut repeats and a homeodomain. In this study, we analyzed genetically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Hair Growth and Disorders
Share to Skin and Cellular Biology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11839809
DOI: 10.1128/mcb.22.5.1424-1437.2002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Ablation of the CDP/Cux Protein C Terminus Results in Hair Cycle Defects and Reduced Male FertilityPMID 11839809Read ↗

Hair defects and pup loss in mice with targeted deletion of the first cut repeat domain of the Cux/CDP homeoprotein gene.Semantic proximity Read ↗

The multiple roles of CUX1: insights from mouse models and cell-based assays.Semantic proximity Read ↗

Regulation of cell proliferation and differentiation in the kidney.Semantic proximity Read ↗

The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle.Semantic proximity Read ↗

Cux2 (Cutl2) integrates neural progenitor development with cell-cycle progression during spinal cord neurogenesis.Semantic proximity Read ↗

Polycystic kidneys caused by sustained expression of Cux1 isoform p75.Semantic proximity Read ↗

Lymphoid apoptosis and myeloid hyperplasia in CCAAT displacement protein mutant mice.Semantic proximity Read ↗

Acceleration of polycystic kidney disease progression in cpk mice carrying a deletion in the homeodomain protein Cux1.Semantic proximity Read ↗

Functional analysis of Drosophila and mammalian cut proteins in files.Semantic proximity Read ↗

Cux1 promotes cell proliferation and polycystic kidney disease progression in an ADPKD mouse model.Semantic proximity Read ↗

Evidence that the satin hair mutant gene Foxq1 is among multiple and functionally diverse regulatory targets for Hoxc13 during hair follicle differentiation.Semantic proximity Read ↗

Transgenic Mice Expressing the p75 CCAAT-Displacement Protein/Cut Homeobox Isoform Develop a Myeloproliferative Disease–Like Myeloid LeukemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.