Article
Quasispecies as predictive factor of rapid, early and sustained virological responses in chronic hepatitis C, genotype 1, treated with peginterferon-ribavirin.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Apr 2008
Salmerón Javier, Casado Jorge, Rueda Paloma Muñoz de, Lafuente Victor, Diago Moises, Romero-Gómez Manuel, Palacios Angel, León Josefa, Gila Ana, Quiles Rosa, Rodriguez Luis, Ruiz-Extremera Angeles
Abstract excerpt
BACKGROUND: The relationship between the complexity of the hypervariable region 1 quasispecies of HCV and responsiveness to therapy is not completely clear. OBJECTIVE: To investigate the importance of quasispecies as a predictive factor of rapid (RVR), early (EVR) and sustained (SVR) virologic response. METHODS: Prospective analysis of 82 patients with chronic hepatitis C, genotype 1, treated with peginterferon...
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