Article
Quasispecies of genotype 4 of hepatitis C virus genomes in Saudi patients managed with interferon alfa and ribavirin therapy.
Annals of Saudi medicine - 1 Jan 2000
Al-Qahtani Ahmed A, Kessie George, Dela Cruz Damian, Al-Faleh Faleh Z, Al-Ahdal Mohammed N
Abstract excerpt
BACKGROUND AND OBJECTIVES: Many patients with hepatitis C virus (HCV) infection do not respond to antiviral treatment, possibly due to viral quasispecies. We aimed to investigate whether the quasispecies population could be used as a predictor of response to therapy in our patients. METHODS: The quasispecies of HCV genotype 4 (HCV-4) were studied in 25 naïve Saudi patients at zero, three, and six months following...
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