Article
Quasispecies as predictive response factors for antiviral treatment in patients with chronic hepatitis C.
Digestive diseases and sciences - 1 May 2006
Salmerón Javier, De Rueda Paloma Muñoz, Ruiz-Extremera Angela, Casado Jorge, Huertas Carlos, Bernal Maria Del Carmen, Rodríguez Luis, Palacios Angel
Abstract excerpt
The object of this study was to evaluate the viral factor, especially the quasispecies, as predictive of sustained virologic response. We studied the quasispecies, genotype, viral load, and hepatitis C (HCV) cAg in 41 patients with chronic hepatitis C treated with interferon and in 84 with interferon and ribavirin. In the interferon group, responders presented a lower viral load. From logistic regression analysis...
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