Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Preimplantation expression of the somatic form of Dnmt1 suggests a role in the inheritance of genomic imprints

25 Jan 2008

Abstract excerpt

BACKGROUND: Identical DNA methylation differences between maternal and paternal alleles in gametes and adults suggest that the inheritance of genomic imprints is strictly due to the embryonic maintenance of DNA methylation. Such maintenance would occur in association with every cycle of DNA replication, including those of preimplantation embryos. RESULTS: The expression of the somatic form of the Dnmt1 cytosine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18221528
DOI: 10.1186/1471-213x-8-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Preimplantation expression of the somatic form of Dnmt1 suggests a role in the inheritance of genomic imprintsPMID 18221528Read ↗

Genomic imprinting disrupted by a maternal effect mutation in the Dnmt1 gene.Semantic proximity Read ↗

Sex-specific exons control DNA methyltransferase in mammalian germ cellsSemantic proximity Read ↗

<i>In vivo</i> stabilization of the Dnmt1 (cytosine-5)- methyltransferase proteinSemantic proximity Read ↗

Abnormal Regulation of DNA Methyltransferase Expression in Cloned Mouse Embryos1Semantic proximity Read ↗

Dynamics of Dnmt1 Methyltransferase Expression and Intracellular Localization during Oogenesis and Preimplantation DevelopmentSemantic proximity Read ↗

Maintenance of genomic methylation patterns during preimplantation development requires the somatic form of DNA methyltransferase 1Semantic proximity Read ↗

Profound phenotypic variation among mice deficient in the maintenance of genomic imprints.Semantic proximity Read ↗

Loss of DNMT1o Disrupts Imprinted X Chromosome Inactivation and Accentuates Placental Defects in FemalesSemantic proximity Read ↗

Lack of involvement of known DNA methyltransferases in familial hydatidiform mole implies the involvement of other factors in establishment of imprinting in the human female germline.Semantic proximity Read ↗

Examination of DNA methyltransferase expression in cloned embryos reveals an essential role for Dnmt1 in bovine developmentSemantic proximity Read ↗

Identification of a region of the DNMT1 methyltransferase that regulates the maintenance of genomic imprints.Semantic proximity Read ↗

Dynamic regulation of DNA methyltransferases in human oocytes and preimplantation embryos after assisted reproductive technologiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.