Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Examination of DNA methyltransferase expression in cloned embryos reveals an essential role for Dnmt1 in bovine development

4 Mar 2011

Abstract excerpt

In studies of somatic cell nuclear transfer (SCNT), the ability of factors within the oocyte to epigenetically reprogram transferred nuclei is essential for embryonic development of the clone to proceed. However, irregular patterns of X-chromosome inactivation, abnormal expression of imprinted genes, and genomic DNA hypermethylation are frequently observed in reconstructed embryos, suggesting abnormalities in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Pluripotent Stem Cells Research
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21480430
DOI: 10.1002/mrd.21306

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Examination of DNA methyltransferase expression in cloned embryos reveals an essential role for Dnmt1 in bovine developmentPMID 21480430Read ↗

Effect of Epigenetic Modifications of Donor Somatic Cells on the Subsequent Chromatin Remodeling of Cloned Bovine Embryos1Semantic proximity Read ↗

Abnormal Regulation of DNA Methyltransferase Expression in Cloned Mouse Embryos1Semantic proximity Read ↗

Unfaithful Maintenance of Methylation Imprints Due to Loss of Maternal Nuclear Dnmt1 during Somatic Cell Nuclear TransferSemantic proximity Read ↗

Genome-Wide Epigenetic Alterations in Cloned Bovine Fetuses1Semantic proximity Read ↗

DNA Methylation Patterns Reflect Epigenetic Reprogramming in Bovine EmbryosSemantic proximity Read ↗

Gene expression in bovine nuclear transfer embryos in relation to donor cell efficiency in producing live offspringSemantic proximity Read ↗

Methylome Dynamics of Bovine Gametes and in vivo Early EmbryosSemantic proximity Read ↗

Delayed and incomplete reprogramming of chromosome methylation patterns in bovine cloned embryosSemantic proximity Read ↗

Epigenetic reprogramming in embryonic and foetal development upon somatic cell nuclear transfer cloningSemantic proximity Read ↗

Effects of DNMT1 and HDAC Inhibitors on Gene-Specific Methylation Reprogramming during Porcine Somatic Cell Nuclear TransferSemantic proximity Read ↗

Bovine DNA Methylation Imprints Are Established in an Oocyte Size-Specific Manner, Which Are Coordinated with the Expression of the DNMT3 Family Proteins1Semantic proximity Read ↗

DNA methylomes of bovine gametes and in vivo produced preimplantation embryosSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.