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Article

Dg-Dys-Syn1 signaling in Drosophila regulates the microRNA profile

29 Oct 2012

Abstract excerpt

BACKGROUND: The Dystrophin Glycoprotein Complex (DGC) is at the center of significant inheritable diseases, such as muscular dystrophies that can be fatal and impair neuronal function in addition to muscle degeneration. Recent evidence has shown that it can control cellular homeostasis and work via Dystrophin signaling to regulate microRNA gene expression which implies that disease phenotypes hide an entourage of...

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PMID: 23107381
DOI: 10.1186/1471-2121-13-26

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