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Article

Clonal accumulation of activated CD8+ T cells in the central nervous system during the early phase of neuroborreliosis.

The Journal of infectious diseases - 15 Mar 2003

Jacobsen Marc, Zhou Dun, Cepok Sabine, Nessler Stefan, Happel Michael, Stei Susanne, Wilske Bettina, Sommer Norbert, Hemmer Bernhard

Abstract excerpt

Borrelia burgdorferi may cause an acute infection of the central nervous system (CNS) that rarely leads to chronic disease. To characterize host immunity to B. burgdorferi in humans, we performed serial T cell receptor (TCR) variable beta (TCRBV) chain analyses in blood and cerebrospinal fluid (CSF) samples from 10 patients with acute neuroborreliosis. In most patients, we found significant differences in TCRBV...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12660943
DOI: 10.1086/368131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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