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Japanese encephalitis virus infection induces changes of mRNA profile of mouse spleen and brain

24 Feb 2011

Abstract excerpt

BACKGROUND: Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus, leading to an acute encephalitis and damage to the central nervous system (CNS). The mechanism of JEV pathogenesis is still unclear. DNA microarray analyses have been recently employed to detect changes in host gene expression, which is helpful to reveal molecular pathways that govern viral pathogenesis. In order to globally identify...

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PMID: 21345237
DOI: 10.1186/1743-422x-8-80

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