Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development and characterization of an animal model of Japanese encephalitis virus infection in adolescent C57BL/6 mouse.

Disease models & mechanisms - 1 Oct 2021

Tripathi Aarti, Banerjee Arup, Vrati Sudhanshu

Abstract excerpt

A mouse-adapted isolate of Japanese encephalitis virus (JEV), designated as JEV-S3, was generated by serially passaging the P20778 strain of the virus in 3- to 4-week-old C57BL/6 mice. Blood-brain barrier leakage was evident in JEV-S3-infected mice, in which viral antigens and RNA were consistently demonstrated in the brain, along with infiltration of activated immune cells, as evidenced by an increased...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Astrocytes
Share to Blood-Brain Barrier
Share to Caspases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Encephalitis, Japanese

Share to Encephalitis Virus, Japanese

Share to Interferons

Share to Microglia

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 34447981
DOI: 10.1242/dmm.049176
PMCID: PMC8543065

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development and characterization of an animal model of Japanese encephalitis virus infection in adolescent C57BL/6 mouse.PMID 34447981Read ↗

Insights into the pathogenesis of herpes simplex encephalitis from mouse models.Semantic proximity Read ↗

Neurovirulence of the Australian outbreak Japanese Encephalitis virus genotype 4 is lower compared to genotypes 2 and 3 in mice and human cortical brain organoidsSemantic proximity Read ↗

A mouse-adapted Yezo virus model for antiviral testing in immunocompetent mice.Semantic proximity Read ↗

Flu Virus Infection in Juvenile Mice Leads to Lifelong Multi-Organ Damage and Parkinsonian Pathological Changes in AgingSemantic proximity Read ↗

A mouse-adapted Yezo virus model for antiviral testing in immunocompetent miceSemantic proximity Read ↗

Modelling tick-borne encephalitis in infant rat mimics important aspects of human diseaseSemantic proximity Read ↗

Myocardial Inflammation and Necrosis in Juvenile Mice Compared with Adult Mice with Coxsackievirus B3 MyocarditisSemantic proximity Read ↗

Neurobiological Alterations Induced by SARS-CoV-2: Insights from Variant-Specific Host Gene Expression Patterns in hACE2-Expressing MiceSemantic proximity Read ↗

Pathological Features of Echovirus-11-Associated Brain Damage in Mice Based on RNA-Seq AnalysisSemantic proximity Read ↗

A mouse model to study Río Negro virus pathogenesis: a neglected member of the Venezuelan equine encephalitis virus complexSemantic proximity Read ↗

A molecularly cloned, live-attenuated japanese encephalitis vaccine SA14-14-2 virus: a conserved single amino acid in the ij Hairpin of the Viral E glycoprotein determines neurovirulence in mice.Semantic proximity Read ↗

Characterisation of a Japanese Encephalitis virus genotype 4 isolate from the 2022 Australian outbreakSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.