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Article

The P450 oxidoreductase, RedA, controls development beyond the mound stage in Dictyostelium discoideum.

BMC developmental biology - 24 Jan 2008

Gonzalez-Kristeller Daniela C, Farage Layla, Fiorini Leonardo C, Loomis William F, da Silva Aline M

Abstract excerpt

BACKGROUND: NADPH-cytochrome-P450 oxidoreductase (CPR) is a ubiquitous enzyme that belongs to a family of diflavin oxidoreductases and is required for activity of the microsomal cytochrome-P450 monooxygenase system. CPR gene-disruption experiments have demonstrated that absence of this enzyme causes developmental defects both in mouse and insect. RESULTS: Annotation of the sequenced genome of D. discoideum...

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Identifiers

PMID: 18218133
DOI: 10.1186/1471-213X-8-8
PMCID: PMC2257935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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