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Article

Thioredoxin reductase is required for growth and regulates entry into culmination of Dictyostelium discoideum.

Molecular microbiology - 1 Sept 2006

Jeong Sun-Young, Choi Chang-Hoon, Kim Ji-Sun, Park Seong-Jun, Kang Sa-Ouk

Abstract excerpt

The thioredoxin system, consisting of thioredoxin, thioredoxin reductase and NADPH, has been well established to be critical for the redox regulation of protein function and signalling. To investigate the role of thioredoxin reductase (Trr) in Dictyostelium discoideum, we generated mutant cells that underexpress or overexpress Trr. Trr-underexpressing cells exhibited severe defects in axenic growth and...

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PMID: 16899077
DOI: 10.1111/j.1365-2958.2006.05329.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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