Article
ABC transporters in Dictyostelium discoideum development.
PloS one - 1 Jan 2013
Miranda Edward Roshan, Zhuchenko Olga, Toplak Marko, Santhanam Balaji, Zupan Blaz, Kuspa Adam, Shaulsky Gad
Abstract excerpt
ATP-binding cassette (ABC) transporters can translocate a broad spectrum of molecules across the cell membrane including physiological cargo and toxins. ABC transporters are known for the role they play in resistance towards anticancer agents in chemotherapy of cancer patients. There are 68 ABC transporters annotated in the genome of the social amoeba Dictyostelium discoideum. We have characterized more than half...
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