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Article

Herpes simplex virus ICP27 increases translation of a subset of viral late mRNAs.

Journal of virology - 1 Apr 2008

Fontaine-Rodriguez Errin C, Knipe David M

Abstract excerpt

The herpes simplex virus (HSV) ICP27 immediate-early protein plays an essential role in the expression of viral late genes. ICP27 is a multifunctional protein and has been reported to regulate multiple steps of mRNA synthesis and processing, including transcription, splicing, and nuclear export. Recently, ICP27 was reported to interact with translation factors and to stimulate translation of the viral late mRNA...

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Identifiers

PMID: 18216091
DOI: 10.1128/JVI.02395-07
PMCID: PMC2268449

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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