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Article

Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27.

Journal of virology - 1 Apr 1990

Rice S A, Knipe D M

Abstract excerpt

Infected-cell protein 27 (ICP27) is a herpes simplex virus type 1 alpha, or immediate-early, protein involved in the regulation of viral gene expression. To better understand the function(s) of ICP27 in infected cells, we have isolated and characterized viral recombinants containing defined alter...

Topics

Animals
DNA Replication
DNA, Viral
Immediate-Early Proteins
Lac Operon
Mutation
RNA, Messenger
RNA, Viral
Simplexvirus
Trans-Activators
Transfection
Viral Proteins
Virus Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2157053
DOI: 10.1128/JVI.64.4.1704-1715.1990
PMCID: PMC249308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2157053-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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