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Article

Experimental transmission of scrapie agent to susceptible sheep by intralingual or intracerebral inoculation.

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire - 1 Jan 2008

Hamir Amir N, Kunkle Robert A, Bulgin Marie S, Rohwer Robert G, Gregori Luisa, Richt Juergen A

Abstract excerpt

Scrapie, a transmissible spongiform encephalopathy (TSE), is a naturally occurring fatal neurodegenerative disease of sheep and goats. This study documents survival periods, pathological findings, and the presence of abnormal prion protein (PrP(Sc)) in genetically susceptible sheep inoculated with scrapie agent. Suffolk lambs (AA/RR/QQ at codons 136, 154, and 171, respectively) aged 4 mo were injected by the...

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Identifiers

PMID: 18214164
PMCID: PMC2117369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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