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Article

Transmission of classical scrapie using lymph node inoculum.

Research in veterinary science - 1 Aug 2024

Frese Alexis J, Greenlee M Heather West, Bian Jifeng, Greenlee Justin J

Abstract excerpt

Scrapie is a fatal, transmissible neurodegenerative disease that affects sheep and goats. Replication of PrPSc in the lymphoid tissue allows for the scrapie agent to be shed into the environment. Brain and retropharyngeal lymph node (RPLN) from a sheep inoculated with the classical scrapie agent was used to compare infectivity of these tissues. Nine Cheviot sheep were used in this study, randomly assigned into...

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Identifiers

PMID: 38970868
DOI: 10.1016/j.rvsc.2024.105348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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