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Article

Complement factor H Y402H polymorphism and characteristics of exudative age-related macular degeneration lesions.

Acta ophthalmologica - 1 Jun 2008

Seitsonen Sanna, Järvelä Irma, Meri Seppo, Tommila Petri, Ranta Päivi, Immonen Ilkka

Abstract excerpt

PURPOSE: The Y402H polymorphism of the complement factor H (CFH) gene is associated with age-related macular degeneration (AMD) in many populations. The reported genotype-phenotype correlations in the CFH Y402H polymorphism have not been pronounced and no studies on the effect of the polymorphism on the subgroups within wet AMD have been performed. In this study, we wanted to evaluate whether the CFH Y402H...

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Source

Identifiers

PMID: 17995985
DOI: 10.1111/j.1600-0420.2007.01050.x

Genes

CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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