Article
Y402H complement factor H polymorphism associated with exudative age-related macular degeneration in the French population.
Molecular vision - 19 Dec 2005
Souied Eric H, Leveziel Nicolas, Richard Florence, Dragon-Durey Marie-Agnès, Coscas Gabriel, Soubrane Gisèle, Benlian Pascale, Fremeaux-Bacchi Veronique
Abstract excerpt
PURPOSE: Identification of genetic factors for age-related macular degeneration (AMD) is of crucial importance in this common cause of blindness. A positive association between Y402H polymorphism of the complement factor H (CFH) gene and AMD has been recently reported in North American populations but not yet in European populations. The exudative form of AMD is rapidly progressive and usually associated with a...
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