Article
Age-dependent prevalence of vascular disease-associated polymorphisms among 2689 volunteer blood donors.
Clinical chemistry - 1 Oct 2001
Hessner M J, Dinauer D M, Kwiatkowski R, Neri B, Raife T J
Abstract excerpt
BACKGROUND: The development of vascular disease involves the interaction of genetic and environmental factors. Because vascular disease is a major contributor to mortality in Western societies, we hypothesized that deleterious polymorphisms associated with hemostasis decrease in frequency among a healthy population as a function of age. METHODS: The frequencies of factor V G1691A Leiden (FVL), factor II (FII)...
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