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Article

Analysis and application of European genetic substructure using 300 K SNP information.

PLoS genetics - 1 Jan 2008

Tian Chao, Plenge Robert M, Ransom Michael, Lee Annette, Villoslada Pablo, Selmi Carlo, Klareskog Lars, Pulver Ann E, Qi Lihong, Gregersen Peter K, Seldin Michael F

Abstract excerpt

European population genetic substructure was examined in a diverse set of >1,000 individuals of European descent, each genotyped with >300 K SNPs. Both STRUCTURE and principal component analyses (PCA) showed the largest division/principal component (PC) differentiated northern from southern European ancestry. A second PC further separated Italian, Spanish, and Greek individuals from those of Ashkenazi Jewish...

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Identifiers

PMID: 18208329
DOI: 10.1371/journal.pgen.0040004
PMCID: PMC2211544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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