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Article

Genome-wide analysis of single nucleotide polymorphisms uncovers population structure in Northern Europe.

PloS one - 1 Jan 2008

Salmela Elina, Lappalainen Tuuli, Fransson Ingegerd, Andersen Peter M, Dahlman-Wright Karin, Fiebig Andreas, Sistonen Pertti, Savontaus Marja-Liisa, Schreiber Stefan, Kere Juha, Lahermo Päivi

Abstract excerpt

BACKGROUND: Genome-wide data provide a powerful tool for inferring patterns of genetic variation and structure of human populations. PRINCIPAL FINDINGS: In this study, we analysed almost 250,000 SNPs from a total of 945 samples from Eastern and Western Finland, Sweden, Northern Germany and Great Britain complemented with HapMap data. Small but statistically significant differences were observed between the...

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PMID: 18949038
DOI: 10.1371/journal.pone.0003519
PMCID: PMC2567036

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