Article
European population substructure: clustering of northern and southern populations.
PLoS genetics - 15 Sept 2006
Seldin Michael F, Shigeta Russell, Villoslada Pablo, Selmi Carlo, Tuomilehto Jaakko, Silva Gabriel, Belmont John W, Klareskog Lars, Gregersen Peter K
Abstract excerpt
Using a genome-wide single nucleotide polymorphism (SNP) panel, we observed population structure in a diverse group of Europeans and European Americans. Under a variety of conditions and tests, there is a consistent and reproducible distinction between "northern" and "southern" European population groups: most individual participants with southern European ancestry (Italian, Spanish, Portuguese, and Greek) have...
Topics
- Arthritis, Rheumatoid
- Cluster Analysis
- Europe
- Gene Frequency
- Genetic Markers
- Genetics, Population
- Humans
- Jews
- Lactase
- New York
- Polymorphism, Single Nucleotide