Article
Vitamin D receptor gene haplotypes and susceptibility to HIV-1 infection in injection drug users.
The Journal of infectious diseases - 1 Feb 2008
de la Torre Manuel Sánchez, Torres Carmen, Nieto Gema, Vergara Salvador, Carrero Antonio José, Macías Juan, Pineda Juan Antonio, Caruz Antonio, Fibla Joan
Abstract excerpt
Vitamin D receptor (VDR) participates in multiple immune functions. Here, we determined whether VDR gene-sequence variations are associated with intersubject differences in the risk of acquiring human immunodeficiency virus type 1 (HIV-1) infection. We assessed this in 460 males exposed to HIV-1 by injection drug use (335 infected and 125 uninfected) and 124 seronegative healthy subjects. Multilocus logistic...
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