Article
Behavioral risk exposure and host genetics of susceptibility to HIV-1 infection.
The Journal of infectious diseases - 1 Jan 2006
Shrestha Sadeep, Strathdee Steffanie A, Galai Noya, Oleksyk Taras, Fallin M Daniele, Mehta Shruti, Schaid Daniel, Vlahov David, O'Brien Stephen J, Smith Michael W
Abstract excerpt
BACKGROUND: Some individuals are readily infected with low human immunodeficiency virus type 1 (HIV-1) exposure, whereas others appear less susceptible, suggesting that host genetics plays a role in the viral entry pathway. The matched case-control study design with measured risk exposures provides an avenue for discovering genes involved in susceptibility to infection. METHODS: We conducted a nested case-control...
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