Article
Host Genetic Background at CCR5 Chemokine Receptor and Vitamin D Receptor Loci and Human Immunodeficiency Virus (HIV) Type 1 Disease Progression among HIV‐Seropositive Injection Drug Users
15 Nov 2001
Abstract excerpt
The effect of polymorphisms on genes encoding the CCR5 chemokine receptor and vitamin D receptor (VDR) in human immunodeficiency virus (HIV) type 1 disease progression was analyzed in a cohort of 185 HIV-seropositive injection drug users. Results confirmed a lack of association in patients with HIV disease between CCR5 wtDelta32 heterozygosity and a slow progression to AIDS and to a CD4 cell count <200...
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