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Article

Gene-environment interaction in progression of AMD: the CFH gene, smoking and exposure to chronic infection.

Human molecular genetics - 1 May 2008

Baird Paul N, Robman Luba D, Richardson Andrea J, Dimitrov Peter N, Tikellis Gabriella, McCarty Catherine A, Guymer Robyn H

Abstract excerpt

A number of risk factors including the complement factor H (CFH) gene, smoking and Chlamydia pneumoniae have been associated with age-related macular degeneration (AMD). However, the mechanisms underlying how these risk factors might be involved in disease progression and disease aetiology is poorly understood. A cohort series of 233 individuals followed for AMD progression over a mean period of 7 years underwent...

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Source

Identifiers

PMID: 18203751
DOI: 10.1093/hmg/ddn018

Genes

CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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